


Apagard M-plus contains a unique form of hydroxyapatite, a mineral naturally found in tooth enamel, that helps fight cavities in three ways:
The toothpaste also contains zeolite, a mineral ingredient that helps prevent the buildup of tartar.
Key Benefits
Apagard M-plus has a mild, neutral mint flavor and does not leave an overpowering aftertaste or alter your sense of taste after brushing.
Why Choose Apagard Toothpaste?
Apagard is a leading Japanese oral-care brand known for its use of hydroxyapatite. The brand dates back to 1985 and is part of Sangi Corporation, a company that has long focused on cavity prevention and tooth remineralization.
In 1974, while working on a NASA project studying the health of astronauts’ teeth and bones in zero gravity, researchers explored new approaches to preventing and addressing tooth decay. Hydroxyapatite, a mineral that makes up a major part of tooth enamel and bone, was identified as a promising restorative material.
Building on the idea that an enamel-like mineral could help fill and restore microscopic areas of damaged enamel, Sangi acquired the relevant patent and began developing hydroxyapatite-based oral-care technology.
After years of research into the properties and applications of hydroxyapatite, Sangi introduced Apagard toothpaste in 1993, bringing its tooth-remineralization approach to everyday oral care.
